Minnesota is a midwestern U.S. state, famously home to more than 10,000 lakes, including Lake Itasca, headwaters of the Mississippi River. Minnesota is the 12th largest in area and the 21st most populous of the U.S. states; nearly 60 percent of its residents live in the Minneapolis–Saint Paul metropolitan area (known as the "Twin Cities"), the center of transportation, business, industry, education, and government and home to an internationally known arts community. The remainder of the state consists of western prairies now given over to intensive agriculture; deciduous forests in the southeast, now partially cleared, farmed and settled; and the less populated North Woods, used for mining, forestry, and recreation.